FIG. 7.

Fetal loss occurs in OVA-bred OT-I mice. A) The number of viable and resorbing fetuses in individual B6-bred and OVA-bred OT-I mice at gd10.5, 13.5, and 17.5 as well as at gd17.5 of a second pregnancy is shown. The percentages of B6-bred and OVA-bred mice with greater than three viable fetuses at each gestational day and for all time points combined (total) are indicated above each graph and at the bottom, respectively. B) The average number of viable and resorbing fetuses in B6-bred and OVA-bred OT-I mice at gd5.5, 10.5, 13.5, and 17.5 is shown with SEM. The average numbers of pups in the first litter and of viable and resorbing fetuses at gd17.5 of a second pregnancy are also shown. For gd5.5, 10.5, 13.5, 17.5, first litter, and gd17.5 of the second pregnancy, n = 6, 6, 8, 6, 6, and 6, respectively, for B6-bred OT-I mice; and n = 7, 7, 9, 7, 6, and 6, respectively, for OVA-bred OT-I mice. Significant differences in the number of viable or resorbing fetuses between B6-bred and OVA-bred at the same gestational day were determined using a Student t-test (*P < 0.05).