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. Author manuscript; available in PMC: 2014 Jun 30.

Published in final edited form as: Mol Psychiatry. 2011 Mar 15;16(6):672–684. doi: 10.1038/mp.2011.14

Freezing behavior during: (a) CFC acquisition, and (b) daily CFC extinction learning and expression. Cal^OE -Dox mice are Cal^OE mice treated with Dox for 3 weeks in adulthood as shown in Fig. 2a. Daily CFC extinction training normalized to that of the controls on Day 1: (c) Dox in adolescence and (d) adulthood studies. * p< 0.01 compared to the control group; # p= 0.01 for Cal^OE vs. Cal^OE.

Freezing behavior during: (a) CFC acquisition, and (b) daily CFC extinction learning and expression. Cal^OE -Dox mice are Cal^OE mice treated with Dox for 3 weeks in adulthood as shown in Fig. 2a. Daily CFC extinction training normalized to that of the controls on Day 1: (c) Dox in adolescence and (d) adulthood studies. * p< 0.01 compared to the control group; # p= 0.01 for Cal^OE vs. Cal^OE.