Table 1. Baseline characteristics.
Variable | Pattern of statin therapy use |
P | |||
Group I | Group II | Group III | Group IV | ||
(n = 2,653) | (n = 309) | (n = 157) | (n = 465) | ||
Age, yrs | 62 ± 13 | 63 ± 12 | 64 ± 14 | 66 ± 13 | < 0.001 |
Male | 2,010 (76) | 213 (69) | 119 (76) | 342 (74) | 0.071 |
Risk factor (%) | |||||
Hypertension | 1,194 (46) | 149 (49) | 77 (50) | 204 (45) | 0.439 |
Diabetes mellitus | 599 (23) | 92 (30) | 30 (20) | 123 (27) | 0.007 |
Current smoker | 1,260 (49) | 129 (44) | 76 (50) | 195 (44) | 0.048 |
Lipid profile | |||||
TC, mg/dL | 188 ± 44 | 178 ± 46 | 181 ± 45 | 168 ± 41 | < 0.001 |
Triglycerides, mg/dL | 133 ± 102 | 133 ± 98 | 133 ± 135 | 116 ± 108 | 0.016 |
HDL-C, mg/dL | 44 ± 13 | 44 ± 17 | 45 ± 17 | 43 ± 13 | 0.124 |
LDL-C, mg/dL | 121 ± 38 | 112 ± 39 | 115 ± 34 | 103 ± 35 | < 0.001 |
Prior PCI | 100 (4) | 23 (7) | 6 (4) | 18 (4) | 0.022 |
Prior angina pectoris | 94 (4) | 10 (3) | 3 (2) | 10 (2) | 0.335 |
Prior CABG | 6 (0.2) | 0 | 0 | 1 (0.2) | 0.789 |
Prior stroke | 153 (6) | 22 (7) | 3 (2) | 27 (6) | 0.147 |
CHF NYHA class > 2 | 16 (0.6) | 4 (1.3) | 2 (1.3) | 5 (1.1) | 0.358 |
Killip class > 1 | 744 (31) | 100 (35) | 37 (26) | 172 (41) | < 0.001 |
LVEF < 45% | 363 (15) | 43 (19) | 18 (13) | 86 (23) | 0.002 |
Systolic BP | 129 ± 29 | 125 ± 31 | 124 ± 25 | 119 ± 31 | < 0.001 |
Diastolic BP | 79 ± 18 | 77 ± 19 | 76 ± 17 | 73 ± 20 | < 0.001 |
Prior statin use | 154 (6) | 18 (6) | 3 (2) | 15 (3) | 0.028 |
Results are presented as mean ± SD or n (%). Patterns of statin therapy use: Group I, statin therapy both during hospitalization and after discharge; Group II, only during hospitalization; Group III, only after discharge; and Group IV, no statin therapy. BP: blood pressure; CABG: coronary artery bypass graft; CHF: congestive heart failure; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; LVEF: left ventricular ejection fraction; NYHA: New York Heart Association; PCI: percutaneous coronary intervention; TC: total cholesterol.