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. 2014 Jul;184(7):2035–2044. doi: 10.1016/j.ajpath.2014.03.005

Figure 3.

Figure 3

Effects of alcohol and betaine on hepatic SR-B1 mRNA expression, plasma membrane 57- and 82-kDa SR-B1 species, relative glycosylation rate, and correlation with cholesterol uptake function of hepatocytes. Six rats per group were pair fed their respective HFC, HFE, and HFEB liquid diets for 8 weeks, after which they were sacrificed and SR-B1 mRNA expression (A), plasma membrane 57- and 82-kDa SR-B1 species (B), relative glycosylation rate (C), and correlation with cholesterol uptake function of hepatocytes (D) were measured as described in Materials and Methods. The data are expressed as means ± SD in each group. Statistical significance of variance was calculated using Tukey's test: ∗P < 0.05, ∗∗P < 0.01 versus HFC; †P < 0.05, ††P < 0.01, and †††P < 0.001 versus HFE.