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. 2014 Jun 23;8:159–168. doi: 10.4137/BBI.S15211

Table 1.

Medicinal plants derived phytochemicals with their antiviral activity against HCV core protein.

PHYTOCHEMICALS PROPERTIES CHEMICAL STRUCTURE FUNCTIONS REFERENCES
EGCG Molecular Weight: 458.37172 [g/mol]
Molecular Formula: C22H18O11
XLogP3: 1.2
H-Bond Donor: 8
H-Bond Acceptor: 11		 graphic file with name bbi-8-2014-159f7.jpg Glycoprotein attachment and replication 30–32
Ladanein Molecular Weight: 314.28946 [g/mol]
Molecular Formula: C17H14O6
XLogP3: 2
H-Bond donor: 2
H-Bond Acceptor: 6		 graphic file with name bbi-8-2014-159f8.jpg HCV entry 33
Naringenin Molecular Weight: 272.25278 [g/mol]
Molecular Formula: C15H12O5
XLogP3-AA: 2.4
H-Bond donor: 3
H-Bond Acceptor: 5		 graphic file with name bbi-8-2014-159f9.jpg Assembly and secretion from core and HCV RNA 34,35
Silybin Molecular Weight: 482.43618 [g/mol]
Molecular Formula: C25H22O10
XLogP3-AA: 2.4
H-Bond Donor: 5
H-Bond Acceptor: 10		 graphic file with name bbi-8-2014-159f10.jpg Entry, replication, Cell to cell spread of secreted viral proteins 27–29,36