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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Birth Defects Res C Embryo Today. 2014 Mar;102(1):101–112. doi: 10.1002/bdrc.21056

FIGURE 7.

FIGURE 7

Muscle paralysis dramatically impaired the development of the supraspinatus tendon-to-bone enthesis in mice. Top: A mature, compositionally graded enthesis (“e”) is seen 56 days postnatally in normal mice (scale bar =200 μm). In contrast, the enthesis in paralyzed shoulders appears disorganized, without a graded fibrocartilaginous transition between the supraspinatus tendon (“s”) and the humeral head bone (“h”). Reproduced with permission from Thomopoulos et al., 2007. Bottom: Maximum stress and modulus were significantly lower in the paralyzed group when compared with the normal and saline groups. Reproduced with permission from Schwartz et al., 2013.