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. 2014 Jul 1;5:316. doi: 10.3389/fmicb.2014.00316

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Copyright © 2014 Duriez, Quillay, Madec, El Costa, Cannou, Marlin, de Truchis, Rahmati, Barré-Sinoussi, Nugeyre and Menu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ratio of IL-1RA/IL-1 β secreted by CD14⁺ dMs after TLR2, TLR3, TLR4, TLR7/8, and TLR9 activation. The IL-1RA/IL-1β ratio of unstimulated and stimulated dMs used for TLR2, TLR3, TLR4, TLR7/8, and TLR9 stimulation is reported (median and range). The IL-1RA/IL-1β ratio of all unstimulated (us) dM samples used for the study is also reported to the left of the graph (median and range). A non-parametric paired permutation was performed between IL-1RA and IL-1β secretion (^ap < 0.05, ^bp < 0.01, and ^cp < 0.001) and between unstimulated and TLR-stimulated dMs IL-1RA/IL-1β ratio (^*p < 0.05, ^**p < 0.01).