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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Hemodial Int. 2012 Jun 20;17(1):24–31. doi: 10.1111/j.1542-4758.2012.00718.x

Table 5.

Multivariable relationship between quartiles of blood pressure measures and cognitive function*

Cognitive Tests Trend p-value Q1 vs. Q4 Q2 vs. Q4 Q3 vs. Q4
β (95% CI) p-value β (95% CI) p-value β (95% CI) p-value
Systolic Blood Pressure Quartiles
MMSE 0.07 0.68 (−0.19, 1.56) 0.12 0.80 (−0.04, 1.65) 0.06 −0.11 (−0.95, 0.74) 0.80
NAART 0.10 −1.13 (−4.67, 2.41) 0.53 2.65 (−0.77, 6.07) 0.13 −1.13 (−4.55, 2.28) 0.51
Percent Retention 0.46 0.84 (−8.36, 10.05) 0.86 5.97 (−2.93, 14.87) 0.19 4.92 (−3.97, 13.80) 0.28
Recognition 0.04 0.48 (−0.43, 1.40) 0.30 0.90 (0.01, 1.79) 0.05 −0.28 (−1.16, 0.61) 0.54
Block Design 0.94 −0.53 (−3.66, 2.61) 0.74 0.43 (−2.59, 3.45) 0.78 0.19 (−2.83, 3.21) 0.90
Digit-Symbol Coding 0.31 0.75 (−4.02, 5.51) 0.76 1.96 (−2.55, 6.47) 0.39 4.02 (−0.49, 8.53) 0.08
Trails A 0.35 −1.74 (−14.60, 11.13) 0.79 −9.75 (−21.98, 2.48) 0.12 −7.58 (−19.72, 4.57) 0.22
Trails B 0.71 8.26 (−24.24, 40.75) 0.62 −7.32 (−38.28, 23.65) 0.64 8.29 (−22.33, 38.91) 0.60
Diastolic Blood Pressure Quartiles
MMSE 0.20 1.01 (0.06, 1.95) 0.04 0.73 (−0.24, 1.69) 0.14 0.42 (−0.43, 1.27) 0.33
NAART 0.18 2.53 (−1.29, 6.36) 0.19 2.66 (−1.24, 6.56) 0.18 3.82 (0.40, 7.25) 0.03
Percent Retention 0.90 2.79 (−7.11, 12.69) 0.58 0.62 (−9.50, 10.74) 0.90 2.76 (−6.08, 11.59) 0.54
Recognition 0.31 0.74 (−0.26, 1.73) 0.15 0.13 (−0.89, 1.15) 0.80 −0.06 (−0.95, 0.82) 0.89
Block Design 0.17 −0.04 (−3.34, 3.26) 0.98 −2.31 (−5.67, 1.06) 0.18 1.21 (−1.76, 4.19) 0.42
Digit-Symbol Coding 0.40 2.04 (−2.99, 7.08) 0.42 −0.91 (−6.00, 4.18) 0.73 2.52 (−1.95, 7.00) 0.27
Trails A 0.56 −8.47 (−22.11, 5.17) 0.22 −0.91 (−14.66, 12.83) 0.90 −4.39 (−16.59, 7.81) 0.48
Trails B 0.88 −5.47 (−39.80, 28.86) 0.76 −5.00 (−39.77, 29.77) 0.78 −12.29 (−42.91, 18.32) 0.43
Pulse Pressure Quartiles
MMSE 0.38 0.56 (−0.34, 1.46) 0.22 0.75 (−0.11, 1.62) 0.09 0.37 (−0.48, 1.21) 0.39
NAART 0.75 0.40 (−3.23, 4.02) 0.83 1.71 (−1.80, 5.21) 0.34 0.04 (−3.39, 3.46) 0.98
Percent Retention 0.66 2.92 (−6.48, 12.32) 0.54 1.20 (−7.94, 10.33) 0.80 5.26 (−3.53, 14.06) 0.24
Recognition 0.47 0.54 (−0.41, 1.48) 0.27 0.52 (−0.40, 1.44) 0.27 0.69 (−0.20, 1.57) 0.13
Block Design 0.96 0.84 (−2.33, 4.00) 0.60 0.60 (−2.46, 3.66) 0.70 0.58 (−2.41, 3.56) 0.70
Digit-Symbol Coding 0.49 0.78 (−4.03, 5.60) 0.75 3.16 (−1.62, 7.94) 0.19 −0.03 (−4.58, 4.52) 0.99