Figure 8. In vivo antitumor efficacy against human SW620 tumor.

(a) Tumor tissue extracted from nude mice after a cycle of therapy. The groups are indicated in Table 2. (b) Tumor inhibition ratios of medication groups with or without thermogel. Student t-tests were performed, and p < 0.05 was regarded as a statistically significant difference, denoted by an asterisk. The p values are 0.024, 0.002, 0.001 between the drug/thermogel and drug groups with respect to 22.5, 45, 90 mg/kg/w IRN doses (n = 6 per group), respectively.