Figure 3.
Mapping of residue positions that differ among eMAT (PDB ID:1RG9), hMAT2A (PDB ID:2PO2) and hMAT1A (PDB ID:2OBV) on the hMAT2A homodimeric structure. Conserved residues among all three MATs are indicated by grey ribbons; residues that differ among all three MATs are highlighted as ball and stick models; and conserved residues among ‘stringent‘ MATs (hMAT1A and eMAT) which differ from the more permissive hMAT2A are highlighted by by yellow ball and stick models. (A color rendering of Figure 3 is provided in the Supporting Information)