Table 3.

Genes with significant expression change in jck bone compared with WT bones (≥ 1.3 fold and p < 0.05, n = 6) at 12 weeks of age

Gene	Description	jck vs WT (fold)
Frzb	frizzled-related protein	−3.54
Wnt16	wingless-type MMTV integration site family, member 16	−2.35
Dkk3	dickkopf 3 homolog (Xenopus laevis)	−2.16
Sost	sclerostin	−2.00
Tgfb3	transforming growth factor, beta 3	−1.90
Wnt10b	wingless-type MMTV integration site family, member 10B	−1.80
Wnt5b	wingless-type MMTV integration site family, member 5B	−1.77
Cdh2	cadherin 2, type 1, N-cadherin (neuronal)	−1.57
Wif1	WNT inhibitory factor 1	−1.55
Sox17	SRY (sex determining region Y)-box 17	−1.38
Ctnnb1	catenin (cadherin-associated protein), beta 1, 88kDa	−1.38
Kremen1	kringle containing transmembrane protein 1	−1.37
Ppp2r5b	protein phosphatase 2, regulatory subunit B′, beta	−1.37
Lrp5	low density lipoprotein receptor-related protein 5	−1.36
Smo	smoothened, frizzled family receptor	−1.34
Sfrp1	secreted frizzled-related protein 1	2.06
Sfrp4	secreted frizzled-related protein 4	1.80
Dkkl1	dickkopf-like 1	1.80
Crebbp	CREB binding protein	1.51
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	1.48
Tgfbr1	transforming growth factor, beta receptor 1	1.43
Pkd1	polycystic kidney disease 1	1.40
Csnk2b	casein kinase 2, beta polypeptide	1.39
Rara	retinoic acid receptor, alpha	1.36
Cd44	CD44 molecule (Indian blood group)	1.33
Csnk1g1	casein kinase 1, gamma 1	1.32
Sox12	SRY (sex determining region Y)-box 12	1.31
Tgfb1	transforming growth factor, beta 1	1.30
Ep300	E1A binding protein p300	1.30