Table 4.
Genes with significant expression change (> 1.2 fold, p < 0.05, n = 6) in bones from 1D11 treated jck mice compared with PBS-treated ones at 12 weeks of age
| Gene | Description | 1D11 vs PBS (fold) | jck vs WT (fold) |
|---|---|---|---|
| Csnk2b | casein kinase 2, beta polypeptide | −1.29 | 1.39 |
| Dvl3 | dishevelled, dsh homolog 3 (Drosophila) | 1.56 | N.S. |
| Pkd1 | polycystic kidney disease 1 | 1.41 | −1.40 |
| Smo | smoothened, frizzled family receptor | 1.34 | −1.34 |
| Ctnnb1 | catenin (cadherin-associated protein), beta 1, 88kDa | 1.31 | −1.36 |
| Appl2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | 1.31 | N.S. |
| Fzd5 | frizzled family receptor 5 | 1.26 | N.S. |
| Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 1.20 | −1.16 |
N.S, not significant