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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: JAMA Neurol. 2014 Apr;71(4):495–498. doi: 10.1001/jamaneurol.2013.6331

Figure 2. Aquaporin-4 Immunoreactivity in Carcinoid Tumor Cells.

Figure 2

A, There is a sharp border between the hypercellular tumor (lower left) and normal liver parenchyma (upper right; hematoxylin and eosin). B, Tumor cells are shaped irregularly with hyperchromatic nuclei and pink cytoplasm (hematoxylin and eosin). C, Aquaporin-4–positive tumor cells (reddish cytoplasm) are relatively sparse and scattered within nests of nonimmunoreactive tumor cells (arrowheads). D, Aquaporin-4 immunoreactivity appears to be predominately cytoplasmic (arrowheads). Scale bars indicate 100 µm (A), 20 µm (B and C), and 10 µm (D).