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In vivo noninvasive spectral CT imaging of sentinel lymph nodes. (a) A cartoon illustrating the site of injection and the area of interest. 150 µL of nanobeacons were injected intradermally in all the cases; (b) regional sentinel lymph nodes were clearly contrasted in conventional CT; (c) K-edge contrast of accumulated gold in the lymph node was selectively imaged with spectral CT.
