FIG. 1.

HIV infection in the NSG-HuPBL mouse model. (a) Representative flow cytometry plot showing the percentage of CD4⁺ and CD8⁺ T cells (of all CD3⁺ T cells) obtained from peripheral blood of NSG mice 14 days after HIV infection or no infection. (b) Representative histogram of HIVp24 flow cytometry staining of peripheral blood from four HIV-infected mice and one noninfected mouse from the experiment in (a). (c) HIV LTR DNA and GAPDH from human splenocytes of five HIV-infected mice (#1–#5) from the experiment in (a). LTR, long terminal repeat; NTC, no template control. Data are representative of three to five mice per group from at least three experiments with similar results.