FIG. 5.

Reversal of tumor outgrowth pathological and β-catenin expression changes in HIV-infected NSG-HuPBL mice after antiretroviral therapy. (a) Representative BrdU and β-catenin staining of the tumor tissue from mice in Fig. 4. (b) Cumulative graph showing proliferation (by BrdU staining) in the tumor tissue of mice from (a). (c) Cumulative graph showing average β-catenin staining from (a). (d, e) Representative flow cytometry plots (d) and cumulative graph (e) showing the percentage of CD4⁺ and CD8⁺ T cells (of all CD3⁺ T cells) obtained from spleens of mice in Fig. 4. Data are representative of four to eight mice per group from at least two experiments with similar results. *p<0.05, **p<0.01, ***p<0.0001.