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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Exp Neurol. 2012 Aug 19;238(2):89–99. doi: 10.1016/j.expneurol.2012.08.008

Figure 4. UPS function in PBMC of LOPD and EOPD patients.

Figure 4

(A) Proteasome 26S and 20S chymotrypsin-like activity. *p<0,05 (B) Densitometry analysis of total ubiquitinated protein content and representative WB. (C) Ubiquitination influence on proteasome activity in LOPD patients: 26S chymotrypsin-like activity do not correlated with ubiquitinated protein content. N=13, Pearson r=0.2840, p=0.3470, r2=0.08066; 20S chymotrypsin-like activity has a significant positive correlation with ubiquitinated protein content. N=13, Pearson r=0.6486, *P<0,05, r2=0,4207.