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. 2014 May 1;12:23. doi: 10.1186/1477-5956-12-23

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Copyright © 2014 Fengos et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Network embedding of the three prototypical receptors in the three cell migration modes. The number (black) and the fraction (red) of proteins for each of the three cell migration modes (squares:HAPTO, diamonds:PDGF, circles:LPA) matching the names of the protein network originating at integrin, RTK and GPCR receptors based on the STRING interaction database for mus musculus. The three rows correspond to consideration of different sets of the experimental data: (A) Phospho-proteomics, (B) Proteomics and (C) Proteomics & Phospho-proteomics. Columns correspond to the neighbouring distance of order one, two or three from the receptors of origin.