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. 2014 Apr 22;14:276. doi: 10.1186/1471-2407-14-276

Figure 4.

Figure 4

Analysis of regulatory effect of E2F1 on MMPs. (A) Immunochistochemistry staining for MMP-2, −7, −9, −16, and VEGFR in SCLC tisssue (Scale bar = 50 μm). (B) Real time PCR and western blotting showed that expressions of MMP-3, −7, −14, −15 were slightly decreased in E2F1i group, but the MMP-9 and −16 were significantly reduced from mRNA and protein levels (**P < 0.01).