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. 2014 Jul;99(7):1191–1196. doi: 10.3324/haematol.2013.096776

Figure 2.

Figure 2.

Cytogenetic and molecular response in patients with and without base-line BCR-ABL1 kinase domain abnormality. CCyR: complete cytogenetic response; MCyR: major cytogenetic response; MMR: major molecular response. aAt baseline, 4 of 77 patients had PCyR, which was among the exclusion criteria for study entry. Therefore, patients with PCyR at baseline were only considered eligible for CCyR and were assessed as not responding if they remained in PCyR. According to these criteria, 3 patients achieving CCyR were assessed as responding. bType of mutation included 1 M244V, 1 M244V+H396R, 4 P-loop (1 G250E, 1 Y253F+E355G, 1 E255K, 1 E255V), 1 A-loop (1 L387M), and 7 other (1 F317L, 1 M351T, 1 E355G, 2 F359V, 1 35bp INS between exons 8 and 9, 1 del 363–386).