Table 4.
Differential expression of the selected gene set in abomasal mucosa (AFM) and draining lymph node (ALN)
| Tissue | Gene | FC Ri vs Ni | FC Ri vs Ru | FC Ni vs Nu | FC Ru vs Nu |
|---|---|---|---|---|---|
| AFM |
IL4 |
4.07* |
2.22 |
0.54 |
1.16 |
| IL13 |
4.51** |
4.79* |
1.06 |
0.93 |
|
| IFNγ |
0.83 |
1.13 |
1.36 |
1.47 |
|
| TNFα |
0.85 |
0.63 |
0.74 |
1.23 |
|
| LGALS15 |
7.02 |
576* |
82.0* |
0.60 |
|
| ITLN2 |
6.97 |
22.4 |
3.22 |
4.94 |
|
| TFF3 |
1.61 |
6.86* |
4.26 |
1.50 |
|
| CCL26 |
Not tested in this tissue |
||||
| TNFRSF4 |
Not tested in this tissue |
||||
| CXCL14 |
Not tested in this tissue |
||||
| PAPPA2 |
1.18 |
0.34 |
0.29* |
1.08 |
|
| ALN | IL4 |
1.22 |
2.33* |
1.91 |
0.81 |
| IL13 |
1.24 |
0.50 |
0.41 |
0.78 |
|
| IFNγ |
0.69 |
0.33** |
0.48 |
1.08 |
|
| TNFα |
0.70* |
0.62 |
0.88 |
1.12 |
|
| LGALS15 |
Not tested in this tissue |
||||
| ITLN2 |
Not tested in this tissue |
||||
| TFF3 |
Not tested in this tissue |
||||
| CCL26 |
1.65 |
1.13 |
0.69 |
0.87 |
|
| TNFRSF4 |
0.68 |
0.59 |
0.87 |
1.11 |
|
| CXCL14 |
1.45 |
1.56 |
1.08 |
0.44 |
|
| PAPPA2 | 1.06 | 0.52 | 0.49* | 0.88 | |
Fold changes (FC) between the four considered groups (resistant allele carriers infected and uninfected (Ri and Ru respectively) and susceptible allele carriers infected and uninfected (Ni and Nu respectively) are provided. Significant differences (nominal p-value < 0.01) are indicated with **, and suggestive differences (nominal p-value < 0.05) are marked as *.