Table 3.

Percent increase in contractile response following EFS + L-NAME

	Jejunum		Colon
EFS (Hz)	Young (n = 8 [3])	Old (n = 20 [6])	Young (n = 10 [3])	Old (n = 30 [8])
1	254 ± 150	206 ± 69.3	104 ± 51.1	81.0 ± 42.6
2	252 ± 167	242 ± 62.0	121 ± 63.4	109 ± 41.1
4	420 ± 101	369 ± 97.5	136 ± 47.2	102 ± 24.2
8	492 ± 137	167 ± 51.3*	149 ± 55.2	154 ± 42.0
16	218 ± 75.7	65.1 ± 15.1	111 ± 31.8	123 ± 43.6
32	104 ± 23.4	33.4 ± 04.60	25.5 ± 7.01	55.8 ± 10.2

In comparison of the percent changes in contractility in response to EFS in the presence of L-NAME, there was no difference seen in the colon of old and young baboons. However, there was significantly less percent excitation observed in the jejunal smooth muscle tissue from old baboons compared to young.

^*p < 0.01, significance was determined using two-way repeated measures anova followed by Bonferonni posttest.