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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2014 Feb 24;276(3):179–187. doi: 10.1016/j.taap.2014.02.011

Figure 3. Effect of DMBA on ovarian expression of chemical biotransformation genes.

Figure 3

PND4 rat ovaries were cultured for 4 d in control media and thereafter exposed to a single 1% DMSO (vehicle control) or DMBA (12.5 nM or 75 nM). Following 1, 2 or 4 additional days of culture, mRNA was isolated and (A) Cyp2e1, (B) Gstp, (C) Gstm, and (D) Ephx1 levels evaluated by quantitative RT-PCR. Values represent fold-change ± SEM relative to a control value of 1, normalized to Gapdh. * = different from control, P < 0.05; # = P < 0.1.