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. 2014 Jun 19;8:14. doi: 10.1186/1754-1611-8-14

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Copyright © 2014 Brie et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Levels of soluble collagen produced by the osteoblasts cultured on titanium implants in serum-free medium (collected on day 21 and 28), simple (OS) and complex (OC) differentiation mediums (collected on day 35). Legend: noninfiltrated, control Ti (Ti control), titanium infiltrated with hydroxyapatite (Ti HA), Ti infiltrated with silicatitanate (Ti SiO₂), cells cultivated on plastic dihes (ctrl) Table: One-way ANOVA analysis reveals statistical differences between the medium of cultivation (SF vs. OS and OC serum-free medium).