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. 2014 Jun 12;10:1339–1346. doi: 10.3762/bjoc.10.136

Table 1.

Antiviral activity of tested molecules calculated as IC50 from the cellular experiments.

Molecule tested IC50

abacavir 5 µM
abacavir derivative a
abacavir-GNP 8 µM
lamivudine 0.35 µM
lamivudine derivative 0.2 µM
lamivudine-GNP 1 µM

aThe abacavir derivative showed the ability to induce viral replication.