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. 2014 Jul 1;9(7):e100761. doi: 10.1371/journal.pone.0100761

Table 3. Cytotoxicity of 8–10, 14, 18 and 21 against DLD-1 colon carcinoma cells and MDA-MB-231 breast carcinoma cells after incubation for 72 h.

IC50/µM
Compound DLD-1 MDA-MB-231
cisplatin 11.2±0.3 22.0±0.6
8 >100 54.1±0.8
9 >200 >100
10 53.8±1.3 37.4±0.6
14 >200 >200
18 >200 >100
21 >200 >200

IC50 values are expressed as mean ± standard error of mean of at least 3 independent experiments.