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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Pediatr Crit Care Med. 2014 Jan;15(1):62–70. doi: 10.1097/PCC.0b013e3182a556ea

Table 2. Relationship Between Mortality and Cerebral Perfusion Pressure Thresholds by Age Group.

CPP Thresholds Survivors (n = 1,681) Nonsurvivors (n = 379) Relative Risk (95% CI) pa
0–11 yr old
n 101 19
 CPP-H eventsb 74 (91.4) 7 (8.6) Reference
 CPP-B eventsc 24 (82.8) 5 (17.2) 1.99 (0.58, 5.80) 0.29
 CPP-L eventsd 3 (30.0) 7 (70.0) 8.10 (3.58, 18.31) < 0.0001

12–17 yr old
n 1 70 17
 CPP-H eventsb 50 (87.7) 7 (12.3) Reference
 CPP-B eventsc 78 (88.6) 10 (11.4) 0.93 (0.37, 2.29) 0.87
 CPP-L eventsd 42 (80.8) 10 (19.2) 1.57 (0.64, 2.81) 0.32

≥ 18 yr old
n 1,410 333
 CPP-H eventsb 701 (84.0) 134 (16.1) Reference
 CPP-B eventsc 562 (83.6) 110 (16.4) 1.02 (0.81, 1.28) 0.87
 CPP-L eventsd 147 (62.3) 89 (37.7) 2.35 (1.88, 2.95) < 0.0001

CPP = cerebral perfusion pressure, CPP-H = high CPP threshold, CPP-B = total time between CPP threshold, CPP-L = total time below the low CPP threshold.

a

Calculated from chi-square test.

b

CPP > 40 mm Hg for 0–5 yr old, > 50 mm Hg for 6–11 yr old, and > 60 mm Hg for > 12 yr old.

c

CPP 30–40 mm Hg for 0–5 yr old, 35–50 mm Hg for 6–11 yr old, and 50–60 mm Hg for > 12 yr old.

d

CPP < 30 mm Hg for 0–5 yr old, < 35 mm Hg for 6–11 yr old, and < 50 mm Hg for > 12 yr old.