Table 2. Relationship Between Mortality and Cerebral Perfusion Pressure Thresholds by Age Group.
CPP Thresholds | Survivors (n = 1,681) | Nonsurvivors (n = 379) | Relative Risk (95% CI) | pa |
---|---|---|---|---|
0–11 yr old | ||||
n | 101 | 19 | ||
CPP-H eventsb | 74 (91.4) | 7 (8.6) | Reference | |
CPP-B eventsc | 24 (82.8) | 5 (17.2) | 1.99 (0.58, 5.80) | 0.29 |
CPP-L eventsd | 3 (30.0) | 7 (70.0) | 8.10 (3.58, 18.31) | < 0.0001 |
| ||||
12–17 yr old | ||||
n | 1 70 | 17 | ||
CPP-H eventsb | 50 (87.7) | 7 (12.3) | Reference | |
CPP-B eventsc | 78 (88.6) | 10 (11.4) | 0.93 (0.37, 2.29) | 0.87 |
CPP-L eventsd | 42 (80.8) | 10 (19.2) | 1.57 (0.64, 2.81) | 0.32 |
| ||||
≥ 18 yr old | ||||
n | 1,410 | 333 | ||
CPP-H eventsb | 701 (84.0) | 134 (16.1) | Reference | |
CPP-B eventsc | 562 (83.6) | 110 (16.4) | 1.02 (0.81, 1.28) | 0.87 |
CPP-L eventsd | 147 (62.3) | 89 (37.7) | 2.35 (1.88, 2.95) | < 0.0001 |
CPP = cerebral perfusion pressure, CPP-H = high CPP threshold, CPP-B = total time between CPP threshold, CPP-L = total time below the low CPP threshold.
Calculated from chi-square test.
CPP > 40 mm Hg for 0–5 yr old, > 50 mm Hg for 6–11 yr old, and > 60 mm Hg for > 12 yr old.
CPP 30–40 mm Hg for 0–5 yr old, 35–50 mm Hg for 6–11 yr old, and 50–60 mm Hg for > 12 yr old.
CPP < 30 mm Hg for 0–5 yr old, < 35 mm Hg for 6–11 yr old, and < 50 mm Hg for > 12 yr old.