A,B: Protein levels of NOX subunits (NOX2, NOX4, p47) were measured by Western blot in A- adipose tissue and B- liver, and bands were quantified. B- NOX activity was measured in liver as described in methods. Results for the HFr (HF) and HFr + EC (EC) were referred to control group values (C). C- NOX2 and NOX4 mRNA were measured by quantitative real-time PCR, normalized against TATA-Box binding protein (TBP) and were referred to control group values (C). D- Protein carbonyls were measured as described in methods. Results are shown as mean ± SEM of 4-8 animals/treatment. *Significantly different from other groups (p<0.05, one way ANOVA test).