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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2014 Apr 16;72:247–256. doi: 10.1016/j.freeradbiomed.2014.04.011

Figure 6. Effects of EC supplementation on parameters of ER stress in epididymal adipose tissue and liver.

Figure 6

The three branches of the UPR response were evaluated by Western blot measuring PERK (Tyr980), eIF2α (Ser51), and IRE1α (Ser724) phosphorylation, sXBP-1 and cleaved ATF6 (cATF6) in A- adipose tissue and B- liver. Bands were quantified and results for the HFr (HF) and HFr + EC (EC) were referred to control group values (C). Phosphorylated/total ratios were calculated for PERK, eIFα and IRE1α; sXBP-1 and cATF6 were normalized to tubulin content. Results are shown as mean ± SEM of 5-8 animals/treatment. *Significantly different from other groups (p<0.05, one way ANOVA test).