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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Am Coll Cardiol. 2013 Jul 17;62(19):1737–1745. doi: 10.1016/j.jacc.2013.05.076

Figure 2. Up-Regulation of IFNβ Expression and IFNβ-Related Pathways in PAR2ko Mice.

Figure 2

Interferon-beta (IFNβ) expression from infected and control (co) (A) pancreas, (B) livers, and (C) hearts measured by qPCR. (A, B) Expression levels are fold to wt at 2 days p.i. (mean was set to 1). (C) Expression levels are fold to wt co (mean was set to 1). Data are mean ± SEM (n = 6 to 8 mice/group). *p < 0.05 for PAR2ko versus wt, †p < 0.05 for PAR2ko versus co mice of the respective genotype and p value according to nonparametric Brunner modeling of longitudinal data. (D) Representative Western blot from infected and co hearts shows phospho-signal transducer and activator of transcription-1 (P-Stat1) and beta-actin (β-actin) at 8 days p.i. Abbreviations as in Figure 1.