Table 4.
Association of alphaB-crystallin with clinicopathological parameters
| |
alphaB-crystallin |
|
||
|---|---|---|---|---|
|
Negative |
Weakly positive |
Strongly positive |
p-value (Pearson chi-square) |
|
| N (%) | N (%) | N (%) | ||
| Randomization arm |
|
|
|
0.556 |
| E-T-CMF |
367 (47.7) |
55 (55.6) |
32 (45.1) |
|
| E-CMF |
126 (16.4) |
8 (8.1) |
13 (18.3) |
|
| ET-CMF |
277 (36.0) |
36 (36.4) |
26 (36.6) |
|
| Age |
|
|
|
0.058 |
| <50 |
301 (39.1) |
47 (47.5) |
33 (46.5) |
|
| ≥50 |
469 (60.9) |
52 (52.5) |
38 (53.5) |
|
| Menopausal status |
|
|
|
0.402 |
| Premenopausal |
351 (45.6) |
51 (51.5) |
33 (46.5) |
|
| Postmenopausal |
419 (54.4) |
48 (48.5) |
38 (53.5) |
|
| Type of surgery |
|
|
|
<0.001 |
| MRM |
548 (71.2) |
53 (53.5) |
43 (60.6) |
|
| Breast conserving |
222 (28.8) |
46 (46.5) |
28 (39.4) |
|
| Tumor size (cm) |
|
|
|
0.937 |
| ≤2 |
232 (30.1) |
35 (35.4) |
21 (29.6) |
|
| 2.1-5 |
435 (56.5) |
55 (55.6) |
40 (56.3) |
|
| >5 |
|
|
|
|
| Histological type |
|
|
|
0.084 |
| Ductal |
586 (76.1) |
80 (80.8) |
61 (85.9) |
|
| Lobular |
89 (11.6) |
6 (6.1) |
2 (2.8) |
|
| Mixed |
59 (7.7) |
10 (10.1) |
3 (4.2) |
|
| Other |
36 (4.7) |
3 (3.0) |
5 (7.0) |
|
| Number of positive nodes |
|
|
|
0.957 |
| 0-3 |
298 (38.7) |
36 (36.4) |
29 (40.8) |
|
| ≥4 |
472 (61.3) |
63 (63.6) |
42 (59.2) |
|
| Histological grade |
|
|
|
<0.001 |
| I-II |
406 (52.7) |
40 (40.4) |
24 (33.8) |
|
| III-Undifferentiated | 364 (47.3) | 59 (59.6) | 47 (66.2) | |
N, number; E, epirubicin; T, paxlitaxel; C, cyclophosphamide; M, methotrexate; F, 5-FU; MRM, modified radical mastectomy.
Significant p-values are shown in bold.