Table 6.
Association of alphaB-crystallin protein expression with all examined markers
| |
alphaB-crystallin |
|
||
|---|---|---|---|---|
| |
N (%) |
N (%) |
N (%) |
|
| Negative | Weakly positive | Strongly positive | p-value (Pearson chi-square) | |
|
ER (n = 938) |
|
|
|
<0.001 |
| Negative |
176 (71.8) |
38 (15.5) |
31 (12.7) |
|
| Positive |
592 (85.4) |
61 (8.8) |
40 (5.8) |
|
|
PgR (n = 940) |
|
|
|
<0.001 |
| Negative |
227 (75.4) |
38 (12.6) |
36 (12.0) |
|
| Positive |
543 (85.0) |
61 (9.5) |
35 (5.5) |
|
|
Ki67 (n = 934) |
|
|
|
<0.001 |
| Low |
267 (89.3) |
17 (5.7) |
15 (5.0) |
|
| High |
499 (78.6) |
81 (12.8) |
55 (8.6) |
|
|
BRCA1 (n = 928) |
|
|
|
0.676 |
| Negative |
707 (81.9) |
91 (10.6) |
65 (7.5) |
|
| Positive |
52 (80.0) |
7 (10.8) |
6 (9.2) |
|
|
BRCA1
(n = 86) |
|
|
|
0.045 |
| WT |
61 (78.2) |
11 (14.1) |
6 (7.7) |
|
| Mutated |
4 (50.0) |
1 (12.5) |
3 (37.5) |
|
|
p53 (n = 918) |
|
|
|
0.002 |
| Negative |
384 (86.3) |
32 (7.2) |
29 (6.5) |
|
| Positive |
370 (78.2) |
66 (14.0) |
37 (7.8) |
|
|
EGFR (n = 928) |
|
|
|
<0.001 |
| Negative |
671 (86.3) |
65 (8.4) |
41 (5.3) |
|
| Positive |
91 (60.3) |
32 (21.2) |
28 (18.5) |
|
|
CK5 (n = 923) |
|
|
|
<0.001 |
| Negative |
694 (86.5) |
67 (8.4) |
41 (5.1) |
|
| Positive |
63 (52.1) |
31 (25.6) |
27 (22.3) |
|
|
CK14 (n = 925) |
|
|
|
<0.001 |
| Negative |
750 (83.9) |
88 (9.8) |
56 (6.3) |
|
| Positive |
9 (29.0) |
10 (32.3) |
12 (38.7) |
|
|
CK17 (n = 909) |
|
|
|
<0.001 |
| Negative |
742 (83.9) |
87 (9.9) |
55 (6.2) |
|
| Positive | 5 (20.0) | 9 (36.0) | 11 (44) | |
WT, wild-type.
Significant p-values are shown in bold.