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. 2014 Jul 1;9(7):e98001. doi: 10.1371/journal.pone.0098001

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© 2014 Trairatphisan et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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[A] The Boolean model of apoptosis by Schlatter et al. [4] consists of 86 nodes with 125 Boolean interactions. The model was analysed with CellNetAnalyzer (CNA) to study the correlations between 10 different inputs from different cytokines stimulations and UVB irradiations towards apoptosis. [B] The normalised experimental dataset were generated based on the experimental data as presented in the original article (see details in File S7). The inverse correlation between UVB irradiation, NFκB and P17 form of activated Caspase 3 (C3ap17) activations, and apoptotic activity is quantitatively observed in the original measurement data.