Fig 3.

Assessment of amyloid deposition by use of florbetapir (Amyvid). The axial PET image on the left shows normal preserved gray-white contrast with the cortical radioactivity less than the adjacent white matter (amyloid-“negative” scan). The axial PET image on the right demonstrates areas of decreased gray-white contrast with increased cortical radioactivity that is comparable to the radioactivity in the adjacent white matter (amyloid-“positive” scan). The florbetapir scan on the right was acquired on a patient with MCI who clinically progressed to dementia with a high biomarker probability of AD, as supported by this amyloid-positive scan and evidence of neuronal injury on structural MR imaging (Fig 1).