Table 1. Mutations of TERT in Esophageal Cancers among 143 Cases.

		Esophageal CA		Healthy controls (21)	Aplastic anemia (21)	Bone marrow failure (22)
		Adenocarcinoma	Squamous cell carcinoma			Dyskeratosis congenita
Total		117	26	528	200	80
A279T†	Homozygous	2	0	0	0	1
	Heterozygous	6	3	10	6	5
	mAF*	4.27%	5.77%	0.90%	1.50%	4.37%
	p value**			<0.01	<0.05	NS***
A1062T‡	Homozygous	0	0	0
	Heterozygous	3	1	7
	mAF*	1.28%	1.92%	0.66%
	p value**			NS***

^†codon 279 GCC/ACC (Ala/Thr).

^‡codon 1062 GCC/ACC (Ala/Thr)].

*mAF (minor allele frequency): frequency of the less frequent allele in a given population.

**p value: compared to both esophageal cancers combined. Fisher's exact test.

***NS: not significant.