Table 2. Gene expression levels of A279T-transduced cells normalized to wtTERT-transduced cells.
EsC1-A279T | EsC2-A279T | |||||
Mean | SEM | p value | Mean | SEM | p value | |
TERT | 0.1 | 0.01 | 5.0E-05 | 0.4 | 0.05 | 5.5E-03 |
CCND1 | 0.1 | 0.01 | 7.5E-06 | ND* | ||
JUNB | 0.1 | 0.01 | 1.5E-03 | 0.7 | 0.08 | 3.3E-02 |
Dkk-1 | 381.8 | 175.96 | 9.8E-02 | 2.8 | 0.38 | 1.9E-02 |
CASP8 | 1.1 | 0.26 | 8.5E-01 | 3.5 | 0.42 | 6.4E-03 |
p57 | 2.2 | 0.19 | 1.0E-02 | 1.7 | 0.15 | 1.9E-02 |
IL-6 | 9.6 | 1.00 | 1.0E-03 | 25.7 | 1.53 | 8.6E-05 |
IL-8 | 1.3 | 0.06 | 5.4E-03 | 5.6 | 0.22 | 3.6E-05 |
BRCA1 | 4.4 | 0.13 | 5.0E-05 | 1.8 | 0.24 | 4.6E-02 |
BRCA2 | 4.9 | 0.33 | 5.1E-04 | 2.4 | 0.32 | 1.5E-02 |
JUNB | 0.1 | 0.01 | 1.5E-03 | 0.7 | 0.08 | 3.3E-02 |
TNF | 0.3 | 0.16 | 5.6E-02 | 28.3 | 2.10 | 2.0E-04 |
*ND: Not detected.