Table 1. The effect of maternal STAT3 deficiency on fetal and placental parameters at day 18 of pregnancy.
Stat3fl/+;Amhr2-cre- | Stat3fl/+;Amhr2-cre+ | Stat3fl/fl;Amhr2-cre- | Stat3fl/fl;Amhr2-cre+ | |
Females pregnant/females mated (%) a | 8/9 (89) | 7/8 (88) | 9/10 (90) | 5/7 (71) |
Mating interval (days) | 6.2±1.6 | 2.9±0.9 | 3.2±0.9 | 2.5±0.7 |
Implantation sites/litter | 7.6±0.4 | 8.4±0.3 | 8.4±0.5 | 9.0±0.9 |
Viable fetuses/litter | 6.9±0.5 (90) a | 7.7±0.4 (92) a | 8.2±0.5 (97) a | 4.2±0.7 (46) b |
Resorbed fetuses/litter | 0.8±0.4 (10) a | 0.7±0.3 (8) a | 0.2±0.1 (3) a | 4.8±0.4 (54) b |
Fetal weight (mg) | 936±28 | 905±23 | 869±20 | 900±49 |
Placental weight (mg) | 110±3 a | 103±2 a | 108±2 a | 135±5 b |
Fetal: placental weight ratio | 8.7±0.4 a | 8.8±0.2 a | 8.1±0.2 ab | 6.9±0.5 b |
Values are mean ± SD. Data were compared by independent samples t-test. Values with different superscript characters were significantly different P<0.05.