. 2014 Jul 1;9(7):e101315. doi: 10.1371/journal.pone.0101315

Table 2. Biochemical parameters (Mean±SD) ^#of the db/db mice with or without dietary selenate supplementation.

Parameter	DMCtrl	DMSe	P Value
Blood
Pretreatment: HbA1c [%(mmol/mol)]	4.2±0.3(21±2)	4.0±0.5(20±6)
At sacrifice: HbA1c [%(mmol/mol)]	5.9±0.6(41±6)	4.4±0.5(25±5)**	0.00516 (0.00331)
Plasma
glucose, mmol/L	29.26±6.52	15.99±5.21***	0.00097
Insulin, pmol/L	11.78±1.67	21.44±8.16^*	0.01640
HOMA-IR index	16.56±3.12	13.56±1.91^NS	0.09395
triglycerides, mmol/L	1.18±0.39	0.61±0.22^*	0.04155
cholesterol, mmol/L	2.74±0.22	3.61±0.60^*	0.04061
low-density lipoprotein, mmol/L	1.91±0.08	2.21±0.23^*	0.01206
malondialdehyde, mmol/L	3.71±0.73	2.72±0.73^NS	0.06013
Pancreatic tissue homogenate
Insulin, pmol/mg protein	282.20±57.24	366.25±58.48^*	0.01668

Mean±SD were calculated for five animals in the DMCtrl group and eight animals in the DMSe group.

*Values significantly different from DMCtrl mice, by the Student t test (*P<0.05, **P<0.01, *** P<0.001).

^NS

indicates the values were not significantly different from DMCtrl mice by the Student t test (P>0.05).

Table 2. Biochemical parameters (Mean±SD) #of the db/db mice with or without dietary selenate supplementation.