Table 4. Median and ranges of lysosomal enzymes activity in fresh CSF.
Enzyme | Median (range) (mU/L) | 25–75 percentile (mU/L) |
α-fucosidase | 626.40 (173.25–883.92) | 392.74–681.23 |
α-mannosidase | 172.98 (7.37–250.44) | 140.3–204.86 |
β-mannosidase | 651.13 (204.63–1158.84) | 388.07–747.78 |
β-galactosidase | 11.39 (4.06–18.67) | 8.29–14.89 |
GCase | 6.52 (1.46–15.20) | 4.06–7.86 |
Cathepsin D | 516.85 (324.76–776.65) | 426.93–595.62 |
Cathepsin E | 14.54 (5.24–33.17) | 10.49–18.24 |
β-hexosaminidase | 3811.63 (1745.40–6919.98) | 2980.07–4614.60 |
Median, ranges, 25-75% percentiles are reported of the enzymatic activities tested in fresh CSF for all the patients included in the study (n = 28). Enzyme activity was measured within 30 minutes from the lumbar puncture.