Figure 5.

In vivo validation of tumor growth inhibition by LiCl treatment.

Notes: After palpable tumors generated by SKOV3 cells developed, ip injections of LiCl (340 mg/kg) were done every 2 days for a total of seven treatments, the tumors were measured, and the tumor volume was calculated once a week (A); The growth of the LiCl-treated tumors was slowed compared with the control; Data are means ± SD (n=4); *P<0.05, ^#P<0.01 versus control; Tumor specimens dissected from the nude mice xenografted with SKOV3 cells at the end of the study (B); Comparison of tumor weight between LiCl group and control (C); Data are means ± SD (n=4); *P,0.05 versus control.

Abbreviations: ip, intraperitoneal; LiCl, lithium chloride; SD, standard deviation.