Table 1.
Demographics and characteristics of men with prostate cancer by TMPRSS2:ETS status of the PCPT study participants.
| All (n=195) | TMPRSS2:ETS positive (n=97) | TMPRSS2:ETS Negative (n=98) | p-value | |
|---|---|---|---|---|
| Mean (SD) | ||||
| Age at Baseline (y) | 60.44 (4.00) | 60.02 (3.84) | 60.85 (4.14) | 0.15 |
| BMI (kg/m2) | 27.35 (3.63) | 27.35 (4.03) | 27.36 (3.21) | 0.99 |
| Alcohol intake (g/d) | 9.49 (14.74) | 8.85 (12.88) | 10.13 (16.42) | 0.54 |
| Baseline PSA (ng/dL) | 2.11 (1.66) | 2.06 (1.76) | 2.15 (1.55) | 0.72 |
| CAG repeat length | 22.0 (2.9) | 21.7 (2.5) | 22.3 (3.2) | 0.12 |
| n (%) | ||||
| Race | 0.15 | |||
| White | 182 (93.33) | 88 (90.72) | 94 (95.92) | |
| Non-white | 13 (6.67) | 9 (9.28) | 4 (4.08) | |
| Family history | 44 (22.56) | 25 (25.77) | 19 (19.39) | 0.29 |
| Diabetes | 10 (5.13) | 6 (6.19) | 4 (4.08) | 0.51 |
| Treatment Arm | 0.09 | |||
| Finasteride | 84 (43.08) | 36 (37.11) | 48 (48.98) | |
| Placebo | 111 (56.92) | 61 (62.89) | 50 (51.02) | |
| Smoking Status | 0.07 | |||
| Never Smoker | 65 (33.33) | 39 (40.21) | 26 (26.53) | |
| Current Smoker | 8 (4.10) | 5 (5.15) | 3 (3.06) | |
| Past Smoker | 122 (62.56) | 53 (54.64) | 69 (70.41) | |
| Physical Activity | 0.90 | |||
| Sedentary | 35 (18.04) | 19 (19.79) | 16 (16.33) | |
| Light | 86 (44.33) | 41 (42.71) | 45 (45.92) | |
| Moderate | 57 (29.38) | 27 (28.13) | 30 (30.61) | |
| Active | 16 (8.25) | 9 (9.38) | 7 (7.14) | |
| Gleason | <0.01 | |||
| Gleason 2–6 | 143 (73.71) | 81 (83.51) | 62 (63.92) | |
| Gleason 7–10 | 51 (26.29) | 16 (16.49) | 35 (36.08) | |