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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Hepatology. 2014 May 28;60(1):278–289. doi: 10.1002/hep.27084

Figure 3. Sox9+ ducts do not differentiate into hepatocytes in DDC or CCl4 injury.

Figure 3

(a) Immunofluorescence for ductal marker Opn (top) and hepatocyte marker Hnf4a (bottom) showed Sox9-CreERT2 marked cells retained ductal fate after regeneration from 5 weeks CCl4 injury (arrows indicate a unique clone). (b) Immunofluorescence for ductal markers A6 (top) and Opn (bottom) continued to co-localize with Sox9-CreERT2 marked clones after 4 weeks of DDC injury. Scale bars = 50μm.