Table 2.
PRN (As-needed) Psychotropic Medication Taken for 1 Month or More by Ever-Recovered and Never-Recovered Patients With Borderline Personality Disorder (BPD) over 14 Years of Prospective Follow-up
| 2 year FU | 4 year FU | 6 year FU | 8 year FU | 10 year FU | 12 year FU | 14 year FU | 16 year FU | RRR Recovery status a Timeb | 95%CI Recovery statusa Timeb | P-value Recovery statusa Timeb | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Use of PRN Medication for Any Reason | ||||||||||||
| Ever-recovered BPD | % (N) | 42 (63) | 26.7 (40) | 23.3 (35) | 31.5 (46) | 21.5 (31) | 28 (40) | 25 (35) | 19.1 (26) | 0.55 0.69 |
0.46, 0.65 0.58, 0.83 |
<0.001 <0.001 |
| Never-recovered BPD | % (N) | 63.2 (79) | 45.4 (54) | 53.5 (61) | 61.5 (67) | 51.4 (54) | 41.6 (42) | 44.9 (44) | 44.2 (42) | |||
| Reasons to Use PRN Among PRN-medicated Patients | ||||||||||||
| PRN to Improve Sleep | ||||||||||||
| Ever-recovered BPD | % (N) | 66.7 (42) | 67.5 (27) | 71.4 (25) | 63.0 (29) | 77.4 (24) | 70 (28) | 57.1 (20) | 65.4 (17) | 1.04 0.91 |
0.92, 1.17 0.76, 1.10 |
NS NS |
| Never-recovered BPD | % (N) | 60.7 (48) | 74.1 (40) | 62.3 (38) | 70.2 (47) | 66.7 (36) | 62 (26) | 47.7 (21) | 59.5 (25) | |||
| PRN to Decrease Anxiety | ||||||||||||
| Ever-recovered BPD | % (N) | 77.8 (49) | 72.5 (29) | 74.3 (26) | 54.4 (25) | 67.7 (21) | 72.5 (29) | 77.1 (27) | 76.9 (20) | 0.91 0.95 |
0.81, 1.01 0.85, 1.06 |
NS NS |
| Never-recovered BPD | % (N) | 92.4 (73) | 72.2 (39) | 78.7 (48) | 58.2 (39) | 74.1 (40) | 85.7 (36) | 81.8 (36) | 88.1 (37) | |||
| PRN to Decrease Agitation | ||||||||||||
| Ever-recovered BPD | % (N) | 69.8 (44) | 67.5 (27) | 54.3 (19) | 32.6 (15) | 48.4 (15) | 57.5 (23) | 62.9 (22) | 53.9 (14) | 0.84 0.80 |
0.74, 0.97 0.68, 0.95 |
0.016 0.009 |
| Never-recovered BPD | % (N) | 79.8 (63) | 74.1 (40) | 72.1 (44) | 37.3 (25) | 61.1 (33) | 81 (34) | 59.1 (26) | 76.2 (32) | |||
Abbreviations: FU= Follow-up RRR = Relative Risk Ratio, CI = Confidence Interval, NS = Non-significant.
a
: Comparison with the ever-recovered and never-recovered borderline patients over the 14 years of follow-up.
b
: Change from 2-year follow-up to 16-year follow-up in the two groups combined.