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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Ann Neurol. 2014 May 28;75(6):837–850. doi: 10.1002/ana.24139

Figure 4.

Figure 4

i.t. gp120 caused visceral hyperalgesia in rats. A. Gp120 significantly increased electromyographic (EMG) activity induced by rectal distention at 24 hrs post i.t. injection (n = 6 rats, ***p<0.001, two way ANOVA vs. baseline). Heat-inactivated gp120 did not cause a significant increase of EMG activity. B. i.t. gp120-induced visceral hyperalgesia maintained on day 2, 7 and 14 post i.t. gp120 injection (n = 6, ***, p<0.001, two way ANOVA vs. baseline). Representative EMGs from the boxed distension pressure are shown to the right of each group.