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. Author manuscript; available in PMC: 2014 Jul 2.
Published in final edited form as: Nature. 2013 Dec 5;504(7478):107–112. doi: 10.1038/nature12822

Figure 6. Cytosolic interactions mediated by ankyrin repeat domains.

Figure 6

a, Cryo-EM density is well fitted by crystal structure of TRPV1 ankyrin repeats 3–6 (PDB code: 2PNN) as a rigid body. Ankyrin repeats 1 and 2 are not observed, presumably due to high flexibility. b, Fingers 3 and inner helices from ankyrin repeat 3 and 4 on the concave surface of the ARD interact with β–strands from the linker and C-terminus of an adjacent subunit.