Figure 2. Food intake, Whole body energy metabolism and urinary energy output in chow, lard-HFD, fish oil-fed and WY-treated mice.

(A) Food intake was measured in every 2–3 days and the average cumulative intake per mouse over the course of the study is shown. Indirect calorimetry was performed in mice and the 24 hr average for energy expenditure (B) and respiratory exchange ratio (C) are presented. Energy output in the urine (D) was assessed by bomb calorimetry. Shown are means ± SEMs, with n = 7–8 per group; b,c p < 0.01, 0.001 vs chow; d,f p < 0.05, 0.001 vs. lard-HFD, *p < 0.05, † p < 0.01, ‡ p < 0.001.