Figure 1.

Experimental design The experimental groups, except for the naïve group, were sensitized by painting with DNFB on days 1, 2, and 3. Mice were challenged by DNFB on days 7, 9, 11, and 13. The naïve group was treated with vehicle (AOO) in the same way. MECA and DEX groups were topically treated with MECA (30, 100, or 300 μg/ear in ethanol and AOO) or DEX (75 μg/ear in ethanol and AOO) on days 8, 10, 12, and 14. All animals were sacrificed on day 15