Table 3.
Motif | Ace2 | Fkh2 | Mbp1 | Mcm1 | Ndd1 | Swi4 | Swi5 | |||||||
B+/C+ | B+/C- | B+/C+ | B+/C- | B+/C+ | B+/C- | B+/C+ | B+/C- | B+/C+ | B+/C- | B+/C+ | B+/C- | B+/C+ | B+/C- | |
ACGCGT (MCB) | 38.4 | 8.3 | 8.2 | 0.0 | ||||||||||
CGCGAAA (SCB) | 7.0 | 1.3 | 19.1 | 2.8 | ||||||||||
AACCAGC (Swi5p) | 5.1 | 0.6 | 2.6 | 0.8 | ||||||||||
GTAAACA (SFF) | 12.9 | 1.8 | 3.1 | 1.4 | 8.3 | 0.6 | 3.5 | 0.1 |
The binomial distribution was used to score motif enrichment in the B+/C+ and B+/C- gene sets for seven cell cycle related transcription factors. The value of -log10(P) is shown only for those combinations of motifs and factors where the motif was significantly overrepresented among the genes bound by the factor. In most cases, the motif is not over-represented in the B+/C- gene group, and in all cases, the over-representation among B+/C- genes is far less significant than among B+/C+ genes.