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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Child Neurol. 2013 Jul 9;28(9):1137–1141. doi: 10.1177/0883073813493667

Figure 3.

Figure 3

Repeated flurothyl-induced seizure activity inhibits the growth of nclf and mnd mice. Wild-type, nclf, and mnd mice at 21 days to 24 days of age underwent kindling (seizure induction by flurothyl once a day for 8 consecutive days) and subsequent retesting (seizure induction by flurothyl once a week for 4 weeks). After the last retesting (at 57 days to 60 days of age), the mice were weighed. Age-matched naïve (no seizure induction), same-strain control mice also were weighed. Columns and bars represent mean ± standard error of the mean (n = 3–5). Repeated seizure activity significantly decreased the total body weight of nclf and mnd mice when compared with naïve same-strain controls (P < .01 for nclf and P < .001 for mnd by unpaired t test). Wild-type animals showed normal growth despite repeated seizure activity (NS: not significant by unpaired t test).