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. 2014 Jun 24;4(6):e004744. doi: 10.1136/bmjopen-2013-004744

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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Meta-analysis of clinical success compares daptomycin with comparator drugs for SSTIs: (A) clinical success (ITT population), (B) clinical success (CE population), (C) daptomycin versus vancomycin for clinical success (CE population). (D) Daptomycin versus vancomycin for clinical success (CE population, excluded the study by Katz et al). The vertical line suggests no difference between daptomycin and comparator drugs. The size of each square represents the proportion of information given by each trial. CE, clinically evaluable; ITT, intention to treat ; SSTI, skin and soft-tissue infection.